Human CellExp™ Cathepsin D, human recombinant

Human CellExp™ Cathepsin D, human recombinant is available at Gentaur for Next week delivery.

Involved in protein degradation in lysosomes

Biomolecule/Target: Cathepsin D

Alternates names: CTSD, Cathepsin D, CPSD, CLN10

Synonyms: CTSD, Cathepsin D, CPSD, CLN10

Background Information: Cathepsin D is also known as CTSD, CPSD, which belongs to the peptidase A1 family. Cathepsin D can be cleaved into the following 2 chains: cathepsin D light chain and cathepsin D heavy chain, which is expressed in the aorta extracellular space (at protein level). The catalytic activity of Cathepsin D is specificity similar to, but narrower than, that of pepsin A. Cathepsin D does not cleave the 4-Gln-|-His-5 bond in B chain of insulin. Cathepsin D involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

NCBI Gene Symbol: CTSD

Gene ID: 1509

NCBI Accession: P07339