Human CellExp™ Carbonic Anhydrase 4/CA4, human recombinant

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SKU:
7484-10
$183
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Description

Human CellExp™ Carbonic Anhydrase 4/CA4, human recombinant is available at Gentaur for Next week delivery.

May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis.

Biomolecule/Target: Carbonic Anhydrase 4/CA4

Alternates names: CA4, Carbonic anhydrase 4

Synonyms: CA4, Carbonic anhydrase 4

Background Information: Carbonic anhydrase 4 (CA4) is also known as Carbonate dehydratase IV, Carbonic anhydrase IV, which belongs to the alpha-carbonic anhydrase family. CA4 may stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid. The enzyme regulation is activated by histamine, L-adrenaline, D-phenylalanine, L- and D-histidine. CA4 can interact with SLC4A4.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

NCBI Gene Symbol: CA4

Gene ID: 762

NCBI Accession: P22748

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Additional Information

Size:
10 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
HEK293 cells
Purity by SDS-PAGE:
≥92%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
<1 EU/μg by LAL method
Activity (Specifications/test method):
N/A
Biological activity:
Measured by its esterase activity. The specific activity is >2 pmol/min/µg.
Results:
Measured by its esterase activity. The specific activity is >2 pmol/min/µg.
Molecular Weight:
This protein is fused with polyhistidine tag at the C-terminus, and has a calculated MW of 31 kDa. The predicted N-terminus is Ala 19. DTT-reduced Protein migrates as 33 kDa in SDS-PAGE.
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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