BioVision Proteins
Human CellExp™ BTLA, Human recombinant
- SKU:
- 9228-50
Description
Human CellExp™ BTLA, Human recombinant is available at Gentaur for Next week delivery.
B- and T-lymphocyte attenuator
Biomolecule/Target: CD273
Alternates names: BTLA, CD272
Synonyms: BTLA, CD272
Background Information: B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.
Reconstitution Instructions: Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/ml
NCBI Gene Symbol: BTLA
Gene ID: 151888
NCBI Accession: NP_001078826.1
Additional Information
Size: |
50 µg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
≥92% |
Assay: |
SDS-PAGE |
Purity: |
≥92% |
Assay 2: |
N/A |
Endotoxin Level: |
< 1 EU/μg |
Activity (Specifications/test method): |
Measured by its binding ability in a functional ELISA |
Biological activity: |
Immobilized Human HVEM, C-Twin Strep Tag at 2 ng/ml (100 µl/well),can bind Human BTLA, Fc Tag with a linear of 0.1-0.5 μg/mL. |
Results: |
N/A |
Molecular Weight: |
This protein is fused with a human IgG1 Fc tag at C-terminus and has a calculated MW of 38.7 kDa. The protein migrates as 45-50 kDa in SDS-PAGE due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |