BioVision Proteins
Human CellExp™ APRIL / TNFSF13, Human Recombinant
- SKU:
- P1372-50
Description
Human CellExp™ APRIL / TNFSF13, Human Recombinant is available at Gentaur for Next week delivery.
Plays a role in the regulation of tumor cell growth.
Biomolecule/Target: TNFSF13
Alternates names: APRIL, TNFSF13, TALL-2, TRDL-1, CD256, TALL2, ZTNF2
Synonyms: APRIL, TNFSF13, TALL-2, TRDL-1, CD256, TALL2, ZTNF2
Background Information: APRIL (a proliferation-inducing ligand) is also known as Tumor necrosis factor ligand superfamily member 13, TALL-2, TRDL-1, CD256, TNFFSF 13, cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. APRIL is a cytokine of the tumor necrosis factor family associated mainly with hematologic malignancies. The closely related TNF family ligands B cell activation factor (BAFF) and a proliferation-inducing ligand (APRIL) serve in the generation and maintenance of mature B-lymphocytes. Both BAFF and APRIL assemble as homotrimers that bind and activate several receptors that they partially share. BAFF-APRIL heteromers of different stoichiometries have distinct receptor-binding properties and activities. In addition, expression of APRIL was regulated by miR-145 in GC cells.
Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 100 µg/ml.
NCBI Gene Symbol: TNFSF13
Gene ID: 8741
NCBI Accession: O75888
Additional Information
Size: |
50 µg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
< 1.0 EU per 1 μg of protein |
Activity (Specifications/test method): |
Measured by its binding ability in a functional ELISA |
Biological activity: |
Immobilized Human BCMA, Mouse IgG2a Fc Tag at 5 μg/mL (100 μL/well) can bind Human APRIL, Fc Tag with a linear range of 0.6-10 ng/mL |
Results: |
N/A |
Molecular Weight: |
42.8 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |