Human CellExp™ APRIL / TNFSF13, Human Recombinant

Human CellExp™ APRIL / TNFSF13, Human Recombinant is available at Gentaur for Next week delivery.

Plays a role in the regulation of tumor cell growth.

Biomolecule/Target: TNFSF13

Alternates names: APRIL, TNFSF13, TALL-2, TRDL-1, CD256, TALL2, ZTNF2

Synonyms: APRIL, TNFSF13, TALL-2, TRDL-1, CD256, TALL2, ZTNF2

Background Information: APRIL (a proliferation-inducing ligand) is also known as Tumor necrosis factor ligand superfamily member 13, TALL-2, TRDL-1, CD256, TNFFSF 13, cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. APRIL is a cytokine of the tumor necrosis factor family associated mainly with hematologic malignancies. The closely related TNF family ligands B cell activation factor (BAFF) and a proliferation-inducing ligand (APRIL) serve in the generation and maintenance of mature B-lymphocytes. Both BAFF and APRIL assemble as homotrimers that bind and activate several receptors that they partially share. BAFF-APRIL heteromers of different stoichiometries have distinct receptor-binding properties and activities. In addition, expression of APRIL was regulated by miR-145 in GC cells.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 100 µg/ml.

NCBI Gene Symbol: TNFSF13

Gene ID: 8741

NCBI Accession: O75888