Human Beta-Catenin

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SKU:
P1626-50
$183
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Description

Human Beta-Catenin is available at Gentaur for Next week delivery.

A component of the Wnt signalling pathway

Biomolecule/Target:

Alternates names: Catenin beta-1; CTNNB1; CTNNB

Synonyms: Catenin beta-1; CTNNB1; CTNNB

Background Information: Beta-catenin is a key downstream component of the canonical Wnt signaling pathway. β-catenin associates with E-cadherin and is involved in regulation of cell adhesion. Stimulation of Wnt pathway can trigger nuclear translocation of β‐catenin. Over expression of β-catenin occurs in various cancers such as colorectal, lung, malignant breast tumor, hepatocellular carcinoma and can be used as a tumor biomarker.

Reconstitution Instructions:

NCBI Gene Symbol:

Gene ID: 1499

NCBI Accession: P35222-1, XP_016861227.1

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Additional Information

Size:
50 μg
Adwords:
False
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
VRAI
Source:
E.coli
Purity by SDS-PAGE:
≥ 92% by SDS-PAGE
Endotoxin Level:
< 0.1 EU/μg of the protein as determined by LAL method
Molecular Weight:
The protein migrates as a ~100-110 kDa band in SDS-PAGE.
Storage Temperature:
-80ºC
Shelf Life:
12 months
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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