BioVision Products
Hemocyanin-Keyhole Limpet (KLH) subunits, powder
- SKU:
- 6286-1
Description
Hemocyanin-Keyhole Limpet (KLH) subunits, powder is available at Gentaur for Next week delivery.
Pure KLH ideal for antibody purification and as a carrier protein and immunogen
Biomolecule/Target:
Alternates names: KLH, keyhole limpett hemocyanin, hemocyanin, Megathura crenulata hemocyanin
Synonyms: KLH, keyhole limpett hemocyanin, hemocyanin, Megathura crenulata hemocyanin
Background Information: Hemocyanins are proteins that use copper binding sites to bind and transport oxygen in a variety of arthropods and mollusks. Hemocyanin is isolated from the hemolymph of the animals. Hemocyanin is one of the strongest antigens known. Hemocyanin has been in use as an immunological reagent for many years. It is used as a carrier protein for antibody production against antigens. Recent advances in immunology and the role immune system plays in diseases have opened a whole new era of product development activities aimed at developing novel therapeutics which is aimed at teaching the body's immune system to fight diseases like cancer, AIDS, etc. The approach involves the use of highly immunogenic molecule like the hemocyanin for non-specific immunostimulation (NSI) or active specific immunostimulation (ASI) using conjugate vaccines, wherein the tumor (disease) specific antigens are covalently bound to carrier protein like KLH and the product used in human clinical studies. Such products are termed “vaccines”. BioVision’s KLH subunits powder has major advantages associated with it, in terms of flexibility of use and the choice of buffer in early developmental studies. These subunits are highly pure and have low endotoxin content.
Reconstitution Instructions: Resuspend in sterile water to a 1 mg/ml concentration
NCBI Gene Symbol: KLH
Gene ID: N/A
NCBI Accession: N/A
Additional Information
Size: |
1 mg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Megathura crenulata |
Recombinant: |
No |
Source: |
Megathura crenulata, Giant keyhole limpet |
Purity by SDS-PAGE: |
≥ 95% |
Assay: |
MPLC-SEC |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
350 and 390 kDa (Two main characteristic bands co-migrating with ferritin) |
Storage Temperature: |
2-8°C |
Shelf Life: |
36 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |
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