GDNF, human recombinant

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SKU:
4097-50
€185
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Description

GDNF, human recombinant is available at Gentaur for Next week delivery.

A promotor of dopamine uptake and survival of midbrain neurons

Biomolecule/Target: GDNF

Alternates names: Glial-Derived Neurotrophic Factor, ATF-1, Astrocyte-derived trophic factor

Synonyms: Glial-Derived Neurotrophic Factor, ATF-1

Background Information: Human GDNF (Glial-Derived Neurotrophic Factor) is a 30.1 kDa protein that specifically promotes dopamine uptake and survival of midbrain neurons. GDNF is a disslphide-linked homodimer, formed by two identical 134 amino acids subunits.

Reconstitution Instructions: Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

NCBI Gene Symbol: GDNF

Gene ID: 2668

NCBI Accession: P39905

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Additional Information

Size:
50 μg
Adwords:
Yes- SG
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
The ED₅₀ as determined by the dose-dependent dopamine uptake by rat ventral mesencephalic cultures was found to be in the range of 4-8 ng/ml.
Results:
4-8 ng/ml.
Molecular Weight:
30.1 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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