Follistatin, mouse recombinant

Follistatin, mouse recombinant is available at Gentaur for Next week delivery.

An autocrine glycoprotein involved in binding and bioneutralization of members of the TGF-β superfamily

Biomolecule/Target:

Alternates names: FS, activin-binding protein, FSH-suppressing protein (FSP)

Synonyms: FS, activin-binding protein, FSH-suppressing protein (FSP)

Background Information: Follistatin is an autocrine acting protein that is expressed by many tissues, but at noteably higher levels in the ovary and skin. Follistatin functions to negatively regulate the signaling of a wide variety of TGF-beta family members (activin, BMPs, myostatin, GDF-11 and TGF-beta 1). Mechanistically, follistatin works as an antagonist by complexing with TGF-beta family members to prevent them from interacting with their signaling receptors. Recombinant mouse follistatin is a nonglycosylated protein, containing 289 amino acids, with a molecular weight of 31.6 kDa.

Reconstitution Instructions: Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/mL, which can be further diluted into other aqueous solutions.

NCBI Gene Symbol: FST

Gene ID: 14313

NCBI Accession: P47931