flt-3-Ligand, murine recombinant

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SKU:
4086-50
€185
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Description

flt-3-Ligand, murine recombinant is available at Gentaur for Next week delivery.

A member of a small family of growth factors that stimulate the proliferation of hematopoietic cells

Biomolecule/Target: Flt-3 Ligand

Alternates names: Fms-related tyrosine kinase 3 ligand, Short name=Flt3 ligand, Short name=Flt3L, SL cytokine

Synonyms: Fms-related tyrosine kinase 3 ligand

Background Information: Flt3-Ligand belongs to a small group of growth factors that regulate proliferation of early hematopoietic cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant form is the transmembrane which is biologically active on the cell surface. The proteolytically cleaved transmembrane isoform generates a soluble form, which is also biologically active. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand alone cannot stimulate proliferation, but synergizes well with other CSFs and interleukins to induce growth and differentiation. Recombinant murine flt3-Ligand is a 16.4 kDa protein containing 144 amino acid residues.

Reconstitution Instructions: Reconstitute in H₂O to a concentration of 0.1 – 1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

NCBI Gene Symbol: Flt3-L

Gene ID: 14256

NCBI Accession: P49772

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Additional Information

Size:
50 μg
Adwords:
Yes- SG
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Mouse
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
Determined by the dose dependent proliferation of mouse AML5 cells
Results:
5-8 ng/ml
Molecular Weight:
16.4 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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