flt-3-Ligand, murine recombinant

flt-3-Ligand, murine recombinant is available at Gentaur for Next week delivery.

A member of a small family of growth factors that stimulate the proliferation of hematopoietic cells

Biomolecule/Target: Flt-3 Ligand

Alternates names: Fms-related tyrosine kinase 3 ligand, Short name=Flt3 ligand, Short name=Flt3L, SL cytokine

Synonyms: Fms-related tyrosine kinase 3 ligand

Background Information: Flt3-Ligand belongs to a small group of growth factors that regulate proliferation of early hematopoietic cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant form is the transmembrane which is biologically active on the cell surface. The proteolytically cleaved transmembrane isoform generates a soluble form, which is also biologically active. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand alone cannot stimulate proliferation, but synergizes well with other CSFs and interleukins to induce growth and differentiation. Recombinant murine flt3-Ligand is a 16.4 kDa protein containing 144 amino acid residues.

Reconstitution Instructions: Reconstitute in H₂O to a concentration of 0.1 – 1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

NCBI Gene Symbol: Flt3-L

Gene ID: 14256

NCBI Accession: P49772