FAK2/PYK2B, Human Recombinant

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SKU:
P1416-50
€185
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Description

FAK2/PYK2B, Human Recombinant is available at Gentaur for Next week delivery.

Protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion.

Biomolecule/Target:

Alternates names: PTK2B, CAK beta, Protein-tyrosine kinase 2-beta

Synonyms: PTK2B, CAK beta, Protein-tyrosine kinase 2-beta

Background Information: FAK2 is a cytoplasmic tyrosine kinase involved in calcium-induced regulation of ion channels and activation of the MAP kinase signaling pathway. It regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. The protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity

Reconstitution Instructions:

NCBI Gene Symbol: 2185

Gene ID: PTK2B

NCBI Accession: Q14289

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Additional Information

Size:
50 µg
Adwords:
False
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
False
Source:
Baculovirus (sf9 Insect Cells)
Purity by SDS-PAGE:
>95%
Assay:
SDS-PAGE
Activity (Specifications/test method):
>20 U/μg (nmol/min/ug) measured by using BioVision ADPsensor™ Universal Kinase Activity Assay Kit K212-100
Molecular Weight:
76.2 kDa (contains N-His tag).
Storage Temperature:
-80ºC
Shelf Life:
12 months
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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