EPO-alpha, human recombinant (new size)

EPO-alpha, human recombinant (new size) is available at Gentaur for Next week delivery.

A glycoprotein hormone that controls erythropoiesis

Biomolecule/Target:

Alternates names: Erythropoietin-α, EPO-α, Epoetin, EP, MGC138142

Synonyms: Erythropoietin-α, EPO-α, Epoetin, EP, MGC138142

Background Information: Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. The differentiation of CFU-E (Colony Forming Unit -Erythroid) cells into erythrocytes can only be accomplished in the presence of EPO. Physiological levels of EPO in adult mammals are maintained primarily by the kidneys, whereas levels in fetal or neonatal mammals are maintained by the liver. EPO also can exert various non-hematopoietic activities, including vascularization and proliferation of smooth muscle, neural protection during hypoxia, and stimulation of certain B cells. BioVision’s Human EPO contains 166 amino acid residues and has a calculated molecular weight of approximately 18.4 kDa. As a result of glycosylation, Recombinant Human EPO migrates with an apparent molecular mass of 37.0 kDa by SDS-PAGE gel, under reducing and non-reducing conditions.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1 to 1.0 mg/ml. This solution can then be diluted into other aqueous buffers containing a carrier protein (like 0.1% BSA) and stored in working aliquots at -20°C to -80ºC for future use.

NCBI Gene Symbol: Epo

Gene ID: 2056

NCBI Accession: P01588