Epidermal Growth Factor (EGF), human recombinant

Epidermal Growth Factor (EGF), human recombinant is available at Gentaur for Next week delivery.

Human EGF from E.Coli, AOF, ≥98% pure, biologically active, cell culture tested.

Biomolecule/Target: EGF

Alternates names: Urogastrone, URG, EGF, epidermal growth factor

Synonyms: Urogastrone, URG, EGF, epidermal growth factor

Background Information: Human epidermal growth factor (EGF) is also known as HOMG4 and URG, and is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation by binding to its receptor EGFR. Epidermal growth factor can be found in human platelets, macrophages, urine, saliva, milk, and plasma. EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. All family members contain one or more repeats of the conserved amino acid sequence. The biological effects of salivary EGF include healing of oral and gastroesophageal ulcers, inhibition of gastric acid secretion, stimulation of DNA synthesis as well as mucosal protection from intraluminal injurious factors such as gastric acid, bile acids, pepsin, and trypsin and to physical, chemical and bacterial agents. Because of the increased risk of cancer by EGF, inhibiting it decreases cancer risk. Recombinant human EGF is a 6.2 kDa protein containing 53 amino acid residues. This recombinant human EGF has an N-terminal His-tag preceding the 53 amino acid sequence (MW = 8.5 kDa)

Reconstitution Instructions: Reconstitute the human EGF in H₂O to a concentration of 0.1-1 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use.

NCBI Gene Symbol: EGF

Gene ID: UniGeneHs.419815

NCBI Accession: Q6QBS2