DPP4/CD26, Human Recombinant

DPP4/CD26, Human Recombinant is available at Gentaur for Next week delivery.

Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation.

Biomolecule/Target:

Alternates names: ADCP-2, ADABP, Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26, TP103, CD_antigen: CD26

Synonyms: ADCP-2, ADABP, Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26, TP103, CD_antigen: CD26

Background Information: DPP4, dipeptidyl peptidase-4 is a complex enzyme expressed on the surface of most cell types and is a serine exopeptidase that cleaves x-proline dipeptides from the N-terminus of polypeptides. DPP4 protein is associated with intracellular signal transduction, apoptosis and plays an important role in tumor biology. There are at least 63 substrates which can bind specifically to DPP4 enzyme including growth factors, chemokines, neuro peptides. Furthermore, DPP4 plays a major role in glucose metabolism by cleaving incretins such as glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). Recombinant human DPP4 protein was expressed with c-terminal His-tag in high-5 cells using baculovirus expression system and purified by using conventional chromatography techniques.

Reconstitution Instructions:

NCBI Gene Symbol: DPP4

Gene ID: 1803

NCBI Accession: P27487