Cytidine deaminase, human recombinant

Cytidine deaminase, human recombinant is available at Gentaur for Next week delivery.

An enzyme that scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis

Biomolecule/Target: Cytidine Deaminase

Alternates names: CDA, CDD, Cytidine aminohydrolase, Cytosine nucleoside deaminase

Synonyms: CDA, CDD, Cytidine aminohydrolase, Cytosine nucleoside deaminase

Background Information: CDA (Cytidine deaminase) is an enzyme that scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. This protein is one of several deaminases responsible for maintaining the cellular pyrimidine pool. The protein also catalyzes the deamination of chemotherapeutic cytosine nucleoside analogs such as Ara-C and 5-azacytidine, which results in the loss of their cytotoxic and antitumor function. It can form homotetramers and is mainly expressed in granulocytes. Recombinant human CDA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Reconstitution Instructions: N/A

NCBI Gene Symbol: CDA

Gene ID: 978

NCBI Accession: P32320