Description
CXCL14/BRAK, human recombinant is available at Gentaur for Next week delivery.
Chemoattractant for monocytes and dendritic cells
Biomolecule/Target: CXCL-14
Alternates names: C-X-C motif chemokine 14 (Chemokine BRAK) (MIP-2G) (Small-inducible cytokine B14)
Synonyms: Chemokine BRAK, MIP-2G, Small-inducible cytokine B15
Background Information: Human Chemokine (C-X-C motif) ligand 14(hCXCL14),also known as breast and kidney-expressed chemokine (BRAK), MIP-2 gamma, kidney-expressed chemokine (KEC), and B cell and monocyte-activating chemokine (BMAC), is a CXC chemokine constitutively expressed in certain normal tissues but is reduced or absent from many established tumor cell lines and human cancers. CXCL14 is known to be a chemo-attractant for monocyte and dendritic cells. CXCL14 inhibits angiogenesis and exhibits antimicrobial activities. Mature human and mouse CXCL14 differ by only 2 residues.
Reconstitution Instructions: Reconstitute the lyophilized recombinant human CXCL14 in sterile 18MΩ-cm H2O not less than 100 μg/ml. This can further be diluted to other aqueous buffers.
NCBI Gene Symbol: CXCL14
Gene ID: 9547
NCBI Accession: O95715
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
≥95% |
Assay 2: |
HPLC |
Endotoxin Level: |
<0.1 ng/μg (1 IEU/μg) |
Activity (Specifications/test method): |
N/A |
Biological activity: |
The ED50 as determined by its ability to induce calcium flux of prostaglandin E2 treated THP1 human acute monocytic leukemia cells was 1.0-10.0 ng/ml. |
Results: |
1.0-10.0 ng/ml |
Molecular Weight: |
~9.4 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |