CXCL14/BRAK, human recombinant

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SKU:
4278-50
€185
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Description

CXCL14/BRAK, human recombinant is available at Gentaur for Next week delivery.

Chemoattractant for monocytes and dendritic cells

Biomolecule/Target: CXCL-14

Alternates names: C-X-C motif chemokine 14 (Chemokine BRAK) (MIP-2G) (Small-inducible cytokine B14)

Synonyms: Chemokine BRAK, MIP-2G, Small-inducible cytokine B15

Background Information: Human Chemokine (C-X-C motif) ligand 14(hCXCL14),also known as breast and kidney-expressed chemokine (BRAK), MIP-2 gamma, kidney-expressed chemokine (KEC), and B cell and monocyte-activating chemokine (BMAC), is a CXC chemokine constitutively expressed in certain normal tissues but is reduced or absent from many established tumor cell lines and human cancers. CXCL14 is known to be a chemo-attractant for monocyte and dendritic cells. CXCL14 inhibits angiogenesis and exhibits antimicrobial activities. Mature human and mouse CXCL14 differ by only 2 residues.

Reconstitution Instructions: Reconstitute the lyophilized recombinant human CXCL14 in sterile 18MΩ-cm H2O not less than 100 μg/ml. This can further be diluted to other aqueous buffers.

NCBI Gene Symbol: CXCL14

Gene ID: 9547

NCBI Accession: O95715

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
≥95%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg (1 IEU/μg)
Activity (Specifications/test method):
N/A
Biological activity:
The ED50 as determined by its ability to induce calcium flux of prostaglandin E2 treated THP1 human acute monocytic leukemia cells was 1.0-10.0 ng/ml.
Results:
1.0-10.0 ng/ml
Molecular Weight:
~9.4 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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