CTSB, mouse recombinant

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SKU:
P1095-10
€185
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Description

CTSB, mouse recombinant is available at Gentaur for Next week delivery.

An anti-protease implicated in myoclonus epilepsy.

Biomolecule/Target: CTSB

Alternates names: Cathepsin B, Ctsb, CB

Synonyms: Cathepsin B, Ctsb, CB

Background Information: CTSB, also known as cathepsin B preproprotein, is a papain-family cysteine protease that is normally located in lysosomes. It has the ability to degrade several extracellular matrix components at both neutral and acidic pH and has been implicated in the progression of several human and rodent tumors progression and arthritis. Recombinant mouse CTSB, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Reconstitution Instructions: N/A

NCBI Gene Symbol: Ctsb

Gene ID: 13030

NCBI Accession: P10605

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Additional Information

Size:
10 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Mouse
Recombinant:
Yes
Source:
Insect cell (Baculovirus)
Purity by SDS-PAGE:
≥90%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
< 1 EU/μg
Activity (Specifications/test method):
Measured by the hydrolysis of 1pmole of Z-Arg-Arg-AMC to Z-Arg-Arg and AMC per minute at pH 6.0 at 37C.
Biological activity:
Specific activity is >2,000 pmol/min/ug and is defined as the amount of enzyme that hydrolyze 1pmole of Z-Arg-Arg-AMC to Z-Arg-Arg and AMC per minute at pH 6.0 at 37C.
Results:
>2,000 pmol/min/ug
Molecular Weight:
36.4 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
0.5 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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