CD1E, human recombinant

(No reviews yet) Write a Review
SKU:
7308-100
£135.37
Frequently bought together:

Description

CD1E, human recombinant is available at Gentaur for Next week delivery.

Mediates the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells

Biomolecule/Target: CD1E

Alternates names: T-cell surface glycoprotein CD1e, CD1A, R2

Synonyms: T-cell surface glycoprotein CD1e, CD1A, R2

Background Information: CD1E is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. CD1E localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Recombinant human CD1E protein, fused to His-tag at N-terminus, was expressed in E.coli.

Reconstitution Instructions: N/A

NCBI Gene Symbol: CD1E

Gene ID: 913

NCBI Accession: P15812

View AllClose

Additional Information

Size:
100 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥85%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
< 1.0 EU per 1 microgram of protein
Activity (Specifications/test method):
N/A
Biological activity:
N/A
Results:
N/A
Molecular Weight:
33.1 kDa (297 aa, 32-305 aa + His tag), confirmed by MALDI-TOF.
Storage Temperature:
-80°C
Shelf Life:
12 months
Concentration:
1 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
View AllClose

0 Reviews

View AllClose