Caspases Group II, Activ Human

Caspases Group II, Activ Human is available at Gentaur for Next week delivery.

Set of recombinant proteases involved in apoptosis

Biomolecule/Target:

Alternates names: N/A

Synonyms: Caspases Group II, Active Human

Background Information: Caspase family consists of more than 10 members. Based on their extended substrate specificities, these enzymes were divided into three major groups: Group I (contains caspase-1,-4,-5), Group II (contains caspase-2,-3,-7), and Group III (contains caspase-6,-8,-9,-10). Evidences have suggested that Group I caspases are involved primarily in the production of inflammatory cytokines, while group II and III enzymes function in apoptosis as effectors and upstream activators, respectively. The group caspases were expressed in E. coli and routinely tested for their ability to enzymatically cleave the substrate VDVAD-pNA (for caspase-2) and DEVD-pNA (for caspase-3 & -7).

Reconstitution Instructions: Reconstitute to 1 unit per µl in PBS.

NCBI Gene Symbol: CASP2 CASP3 CASP7

Gene ID: CASP2- 835 CASP3- 836 CASP7- 840

NCBI Accession: CASP2- P42575 CASP3- P42574 CASP7- P55210