Carbonic anhydrase-8, human recombinant

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SKU:
P1047-50
$719.07
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Description

Carbonic anhydrase-8, human recombinant is available at Gentaur for Next week delivery.

A protein lacks carbonic anhydrase activity, involved in Cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3).

Biomolecule/Target: CA8

Alternates names: CA-VIII, CALS, CAMRQ3, CARP, CA8

Synonyms: CA-VIII, CALS, CAMRQ3, CARP, CA8

Background Information: CA8 was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, this protein lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). It continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. Defects in CA8 are the cause of cerebellar ataxia mental retardation and dysequilibrium syndrome type 3 (CMARQ3). Recombinant human CA8 protein fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Reconstitution Instructions: N/A

NCBI Gene Symbol: CA8

Gene ID: 767

NCBI Accession: P35219

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
> 90%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
Measured by its ability to hydrolyze 1.0 pmole of 4-nitrophenyl acetate to 4-nitrophenol per minute at pH 7.5 at 37C.
Biological activity:
Specific activity is defined as the amount of enzyme that hydrolyze 1.0 pmole of 4-nitrophenyl acetate to 4-nitrophenol per minute at pH 7.5 at 37C.
Results:
>450 pmol/min/ug
Molecular Weight:
35.5 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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