BMP-9/GDF-2, human recombinant

BMP-9/GDF-2, human recombinant is available at Gentaur for Next week delivery.

Plays an important role during prenatal development and postnatal growth, remodeling and maintenance of a variety of tissues and organs

Biomolecule/Target: BMP-9

Alternates names: Growth/Differentiation Factor-2, BMP-9

Synonyms: Growth/Differentiation Factor-2, BMP-9

Background Information: GDF-2 belongs to the TGF-β cytokine family whose members play an important role during prenatal development and postnatal growth, remodeling and maintenance of a variety of tissues and organs. GDF-2 is expressed mainly in non-parenchymal cells of the liver, but is also found in other various cells and tissues. GDF-2 can signal through the ALK1 receptor and has been implicated in a number of physiologic events. These include regulation of the hepatic reticulo-endothelial system, glucose homeostasis, and iron homeostasis, as well as the inhibition of angiogenesis. Recombinant human GDF-2 is a 24.1 kDa disulfide linked homodimeric protein consisting of two 110 amino acid polypeptide chains.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

NCBI Gene Symbol: GDF2

Gene ID: 2658

NCBI Accession: Q9UK05