BMP-6, human recombinant

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SKU:
4911-50
€185
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Description

BMP-6, human recombinant is available at Gentaur for Next week delivery.

Induces all osteogenic markers in mesenchymal stem cells.

Biomolecule/Target:

Alternates names: VGR, VGR1, BMP-6, VG-1-related protein

Synonyms: VGR, VGR1, BMP-6

Background Information: BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Recombinant human BMP-6 produced from E. coli contains a mixture of monomer (15 kDa), dimer (30 kDa), and multimers. The dimer is an active polypeptide chain containing 2X142 amino acid residues.

Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in sterile 20 mM acetic acid. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

NCBI Gene Symbol: BMP6

Gene ID: 654

NCBI Accession: P22004

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
BioVision’s recombinant human BMP-6 is biologically active. The ED₅₀ as determined by dose-dependent induction of alkaline phosphatase activity with C2C12 cells is in the range of 2-12 µg/ml.
Results:
2-12 µg/ml
Molecular Weight:
monomer (15 kDa), dimer (30 kDa)
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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