Description
BMP-2, Human Recombinant is available at Gentaur for Next week delivery.
A protein involved in the hedgehog and TGF beta signaling pathway
Biomolecule/Target: BMP-2
Alternates names: BMP-2, BMP2A, bone morphogenetic protein2
Synonyms: BMP-2, BMP2A, bone morphogenetic protein2
Background Information: BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. In addition to its osteogenic activity, BMP-2 also plays an important role in cardiac morphogenesis. BMP-2 is expressed in a variety of tissues such as lung, spleen, brain, liver, prostate ovary, and small intestine. Recombinant human BMP-2 is a 26 kDa homodimeric protein consisting of two 115 amino acid polypeptide chains
Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in H₂O containing BSA (50 ug BSA per 1 ug of protein). This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
NCBI Gene Symbol: BMP 2
Gene ID: 650
NCBI Accession: P12643
Additional Information
Size: |
50 μg |
Adwords: |
Yes |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥98% |
Assay: |
SDS-PAGE |
Purity: |
≥98% |
Assay 2: |
HPLC |
Endotoxin Level: |
<0.1 ng/μg |
Activity (Specifications/test method): |
N/A |
Biological activity: |
The ED50 as determined by the dose-dependent cytolysis of ADTC cells is ≤ 2.8 µg/ml. |
Results: |
< 50 ng/ml |
Molecular Weight: |
26.0 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |