BMP-11, human recombinant

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SKU:
4576-50
£135.37
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Description

BMP-11, human recombinant is available at Gentaur for Next week delivery.

A protein that controls anterior-posterior patterning by regulating the expression of Hox genes

Biomolecule/Target: BMP-11

Alternates names: bone morphogenetic protein 11, BMP11, BMP 11, Growth/Differentiation Factor-11, GDF-11, GDF11, GDF 11

Synonyms: bone morphogenetic protein 11, BMP11, BMP 11, Growth/Differentiation Factor-11, GDF-11, GDF11, GDF 11

Background Information: BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Recombinant human BMP-11 is N-terminus His-tagged protein with a molecular weight of 32.6 kDa (for homodimeric) and 16.2 (for monomeric) consisting of 136 amino acid polypeptide chains.

Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in H₂O containing BSA (50 μg BSA per 1 μg of protein). This solution can then be diluted into other aqueous buffers.

NCBI Gene Symbol: BMP11/GDF11

Gene ID: 10220

NCBI Accession: O95390

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Additional Information

Size:
50 μg
Adwords:
Yes
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
The protein is biologically active as determined by its ability to induce alkaline phosphatase production by C2C12 cells. The ED₅₀ is in the range of 0.4-4 µg/ml.
Results:
0.4-4 µg/ml
Molecular Weight:
32.6 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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