BioVision Proteins
Beta-lactaminase, Human Recombinant
- SKU:
- P1196-20
Description
Beta-lactaminase, Human Recombinant is available at Gentaur for Next week delivery.
Serine beta-lactamase with a substrate specificity for cephalosporins
Biomolecule/Target: ampC
Alternates names: ampC, ampA, Cephalosporinase
Synonyms: ampC, ampA, Cephalosporinase
Background Information: AmpC, also known as Beta-lactamase, is the most widespread resistance mechanism to beta-lactam antibiotics, such as the penicillins and the cephalosporins. These antibiotics have a common element in their molecular structure: a four-atom ring known as a beta-lactam. The lactamase enzyme breaks that ring open, deactivating the molecule's antibacterial properties. Recombinant E.coli beta-lactamase protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Reconstitution Instructions: N/A
NCBI Gene Symbol: ampC
Gene ID: 948669
NCBI Accession: P00811
Additional Information
Size: |
20 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E.coli |
Purity by SDS-PAGE: |
> 95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
Measured by its ability to hydrolyze 1.0 µmole of Nitrocefin per minute at pH 7.0 at 37C. |
Biological activity: |
Specific activity is >700 units/mg |
Results: |
>700 units/mg |
Molecular Weight: |
41.8 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |