Beta 2 Microglobulin, Human Urine

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SKU:
P1432-250
$719.07
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Description

Beta 2 Microglobulin, Human Urine is available at Gentaur for Next week delivery.

Biomolecule/Target:

Alternates names: B2M, BMG, beta-2M

Synonyms: B2M, BMG, beta-2M

Background Information: B2M, also known as β2-Microglobulin or CDABP0092, is a component of MHC class I molecules found expression in all nucleated cells (excludes red blood cells). The major function of MHC class I moleculesis is to display fragments of proteins from within the cell to T-cells and cells containing foreign proteins will be attacked. B2M(β2-Microglobulin) is a low molecular weight protein. It was demonstrated that B2M(β2-Microglobulin) was localized in the membranes of nucleated cells and was found to be associated with HL-A antigens. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinaemia, renal failure, or kidney transplants. For the diagnosis of multiple myeloma, the serum β2-microglobulin level is one of the prognostic factors incorporated into the International Staging System. The serum β2-microglobulin level is elevated (>2.7 mg/L) in 75% of patients at the time of diagnosis.

Reconstitution Instructions:

NCBI Gene Symbol: B2M

Gene ID: 567

NCBI Accession: P61769

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Additional Information

Size:
250 µg
Adwords:
False
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
False
Source:
Human urine
Purity by SDS-PAGE:
>98%
Assay:
SDS-PAGE.
Molecular Weight:
12 kDa
Storage Temperature:
4.0 °C
Shelf Life:
12 months
Appearance:
Liquid protein
Handling:
Centrifuge the vial prior to opening.
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