BAFF Receptor, human recombinant

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SKU:
4452-50
€185
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Description

BAFF Receptor, human recombinant is available at Gentaur for Next week delivery.

A TNF receptor that specifically interacts with BAFF

Biomolecule/Target: BAFF Receptor

Alternates names: Tumor necrosis factor receptor superfamily member 13C, B-cell-activating factor receptor, BAFF receptor, Short name=BAFF-R, BLyS receptor 3, CD_antigen=CD268

Synonyms: human BAFF Receptor, h-BAFF Receptor, rh-BAFF Receptor, recombinant human BAFF Receptor, recombinant BAFF Receptor

Background Information: BAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFFR/BAFF signaling plays a critical role in B cell survival and maturation. Recombinant human BAFFR is a 76 amino acid polypeptide (7.7 kDa) corresponding to the extraCellular portion of the full BAFFR protein.

Reconstitution Instructions: Reconstitute in sterile H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or –20°C for future use.

NCBI Gene Symbol: TR13C

Gene ID: 115650

NCBI Accession: Q96RJ3

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
≥95%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
Determined by its ability to block BAFF induced mouse splenocyte survival. The expected ED₅₀ for this effect is typically 1-5 µg/ml in the presence of 1 µg/ml human soluble BAFF.
Results:
1-5 µg/ml
Molecular Weight:
7.7 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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