AITRL, Human Recombinant

AITRL, Human Recombinant is available at Gentaur for Next week delivery.

Regulator of T-cell proliferation and survival, and involved in the interaction between T lymphocytes and endothelial cells

Biomolecule/Target: AITRL

Alternates names: Activation-induced TNFR member Ligand, TNFSF18, GITRL, TL-6

Synonyms: Activation-induced TNFR member Ligand, TNFSF18, GITRL, TL-6

Background Information: AITRL, a member of the TNF superfamily, is expressed in endothelial cells, and signals through the AITR receptor. AITRL regulates T-cell proliferation and survival, and effectuates the interaction between T lymphocytes and endothelial cells. The AITRL gene codes for a type II transmembrane protein comprised of 177 amino acids, including a 28 amino acid cytoplasmic region, a 21 amino acid transmembrane domain and a 128 amino acid extracellular domain. Recombinant human soluble AITRL is a 14.4 kDa protein, containing 127 amino acid residues corresponding to the extracellular domain of AITRL.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

NCBI Gene Symbol: TNFSF18

Gene ID: 8995

NCBI Accession: Q9UNG2