Description
4-1BBR, human recombinant is available at Gentaur for Next week delivery.
A transmembrane cytokine receptor
Biomolecule/Target: 4-1BB Receptor
Alternates names: TNFRSF9, CD137 antigen, T-cell antigen ILA
Synonyms: TNFRSF9, CD137 antigen, T-cell antigen ILA
Background Information: Human 4-1BB Receptor (4-1BBR) is an inhibitor of 4-1BBL and can block 4-1BBL bioactivity. Recombinant human 4-1BBR is a 17.8 kDa protein containing 167 amino acid residues of extraCellular domain of 4-1BBR without signal peptide (Gene accession # NP_001552).
Reconstitution Instructions: Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
NCBI Gene Symbol: TNR9
Gene ID: 3604
NCBI Accession: Q07011
Additional Information
Size: |
1 mg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥98% |
Assay: |
SDS-PAGE |
Purity: |
≥98% |
Assay 2: |
HPLC |
Endotoxin Level: |
<0.1 ng/μg |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Determined by its inhibitory effect of the 4-1BBL mediated stimulation of IL-8 production by human PBMC. About 90% of inhibition was seen using a concentration of 1 µg for both 4-1BBL and 4-1BBR. |
Results: |
1 µg |
Molecular Weight: |
17.8 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |
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