PicoProbeTM Methylglyoxal Assay Kit (Fluorometric)

PicoProbeTM Methylglyoxal Assay Kit (Fluorometric)is available at Gentaur for Next week Delivery.

First fluorometric kit in the market that can detect Methylglyoxal in samples.

Description:

Methylglyoxal ( mg, 2-oxopropanal, pyruvic aldehyde), a by-product of glycolysis, is a highly toxic, reactive dicarbonyl compound. It causes non-enzymatic glycation of proteins which yields irreversible advanced glycation end products (AGEs), leading to cross-linking or degradation of proteins. mg is associated with several pathologies including diabetes, aging and neurodegenerative diseases. Furthermore, recent studies have suggested that mg may induce carbonyl stress-type schizophrenia. BioVision’s PicoProbeTM Methylglyoxal Assay Kit (Fluorometric) can detect mg using an enzyme-coupled reaction which reduces the fluorogenic probe. The reduced fluorophore produces a stable signal (Ex/Em= 535/587nm), which is directly proportional to the amount of mg in samples. The assay is simple, reproducible and can specifically detect as low as 6 pmol of mg in a 100 µl reaction.

Applications: This Kit provides a simple, highly sensitive in vitro assay for detecting Methylglyoxal levels in biological samples.

Sample Typ:e • Tissue Homogenates and Cell Lysates: Mouse Liver, Rat Brain, Jurkat cells, etc. • Biological Fluids: Cerebrospinal Fluid (CSF), etc.

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Features and Benefits:

This Kit provides a simple, highly sensitive in vitro assay for detecting Methylglyoxal levels in biological samples.