PicoProbe™ Fructose-1,6-Bisphosphatase Inhibitor Screening Kit (F)

PicoProbe™ Fructose-1,6-Bisphosphatase Inhibitor Screening Kit (F)is available at Gentaur for Next week Delivery.

Simple assay for high-throughput screening of FBP1 inhibitors/activators.

Description:

Fructose-1,6-bispohphatase (FBP1) is responsible for the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate in the rate determining step of gluconeogenesis. FBP1 is a tetramer that plays a role in regulating adiposity and appetite. FBP1 has emerged as an important therapeutic target to treat diabetes type 2 to regulate glucose levels during gluconeogenesis. In BioVision’s FBP1 Inhibitor Screening Kit, human FBP1 hydrolyzes fructose-1,6-bisphosphate to fructose-6-phosphate which oxidizes and reacts with a fluorogenic probe, that is detected at Ex/Em= 535/587 nm. The assay is fast, sensitive, high-throughput compatible and provides a quick and sensitive way for screening, studying and characterizing potential novel inhibitors of FBP1

Applications: Screening/characterizing/studying FBP1 inhibitors/activators

Sample Typ:e Not Applicable

Alternate Name:

Features and Benefits:

• Simple and reliable test to screen FBP1 inhibitors/activators • High-throughput compatible • Includes Inhibitor Control (AMP)