DNA Damage Quantification Colorimetric Kit

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SKU:
K253-25
€495
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Description

DNA Damage Quantification Colorimetric Kitis available at Gentaur for Next week Delivery.

Detects AP sites.

Description:

Apurinic/apyrimidinic (AP) sites are one of the major types of DNA lesions formed during the course of base excision and repair of oxidized, deaminated or alkylated bases. It has been estimated that about 2x105 base lesions are generated per cell per day. The level of AP sites in cells can be a good indicator of DNA lesion and repair against chemical damage and cell aging. The DNA Damage Quantification Kit utilizes the ARP (Aldehyde Reactive Probe) reagent that reacts specifically with an aldehyde group which is the open ring form of the AP sites. After treating DNA containing AP sites with ARP reagents, AP sites are tagged with biotin residues, which can be quantified using avidin-biotin assay followed by a colorimetric detection. The kit provides the necessary reagents for convenient determination of abasic sites in purified DNA sample in 96-well plate format.

Applications:

Sample Typ:e Purified damaged DNA

Alternate Name:

Features and Benefits:

• Kit provides all necessary reagents for 96-well plate format

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Additional Information

Size:
25 assays
Storage Conditions:
4°C-20°C
Shipping Conditions:
gel pack
Shelf life:
12 months
Category:
Apoptosis
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