Cyclooxygenase-1 (COX-1) Inhibitor Screening Kit (Fluorometric)

(No reviews yet) Write a Review
SKU:
K548-100
Availability:
Next Week Delivery
€375
Frequently bought together:

Description

Cyclooxygenase-1 (COX-1) Inhibitor Screening Kit (Fluorometric)is available at Gentaur for Next week Delivery.

Simple assay to screen/study/characterize COX-1 Inhibitors.

Description:

Cyclooxygenase (COX), also known as prostaglandin-endoperoxide synthase (PTGS, EC 1.14.99.1), is an enzyme that is responsible for the formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane. COX is the central enzyme in the biosynthetic pathway to prostanoids from arachidonic acid. There are two known isoenzymes: COX-1 and COX-2. COX-1 is constitutively expressed in many tissues and is the predominant form in gastric mucosa and in kidney. COX-2 is not expressed under normal conditions in most cells, but elevated levels are found during inflammation. Pharmacological inhibition of COX by non-steroidal anti-inflammatory drugs (NSAID) can provide relief from the symptoms of inflammation and pain. BioVision’s COX-1 Inhibitor Screening Kit offers a rapid, simple, sensitive, and reliable test suitable for high-throughput screening of COX-1 inhibitors. The assay is based on the fluorometric detection of Prostaglandin G2, the intermediate product generated by the COX enzyme.

Applications: Screening/studying/characterizing COX-1 inhibitors.

Sample Typ:e

Alternate Name: Prostaglandin-Endoperoxide Synthase 1 Inhibitor Screening Kit (Fluorometric), PTGS1 Inhibitor Screening Kit (Fluorometric)

Features and Benefits:

• Simple method to screen COX-1 inhibitors • High-throughput • Includes Inhibitor Control, SC560

View AllClose

Additional Information

Size:
100 assays
Storage Conditions:
4°C-20°C
Shipping Conditions:
gel pack
Shelf life:
12 months
Detection Method:
Fluorescence (Ex/Em 535/587 nm)
Category:
Signal Transduction, COX-1
View AllClose

0 Reviews

View AllClose