CETP Inhibitor Screening Kit (Fluorometric) II

CETP Inhibitor Screening Kit (Fluorometric) IIis available at Gentaur for Next week Delivery.

The most advanced kit on the market - includes human CETP enzyme and CETP inhibitor Anacetrapib.

Description:

Cholesteryl ester transfer protein (CETP) is a plasma protein that transfers a cholesteryl ester from HDL to LDL or VLDL in exchange for a triglyceride. HDL plays an important role in lipid metabolism and cardiovascular health. HDL transports cholesterol to the liver for excretion or to steroidogenic tissues for steroid synthesis. HDL also plays an important role in the reverse cholesterol transport pathway, removing cholesterol from lipid-filled macrophages, protecting against atherosclerosis. Because of this function, CETP is viewed as a target to increase HDL, with CETP inhibition being an active area of research and several CETP inhibitors at various stages of drug development. BioVision’s CETP Inhibitor Screening Kit uses a self-quenched fluorescent neutral lipid that can be measured when transferred to an acceptor molecule. The fluorometric intensity is directly proportional to the amount of neutral lipid transfer. Enriched Human CETP from plasma is included for screening. A CETP inhibitor (Anacetrapib) is included as a positive control.

Applications: • Screening/studying/characterizing CETP inhibitors

Sample Typ:e Cell and tissue culture supernatants, urine, plasma, serum, as well as many other biological fluids

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Features and Benefits:

• The most advanced kit on the market - includes human CETP enzyme and CETP inhibitor Anacetrapib for ultimate user-convenience. • Simple and sensitive assay • High-Throughput adaptable