Cathepsin E Inhibitor Screening Kit (Fluorometric)

Cathepsin E Inhibitor Screening Kit (Fluorometric)is available at Gentaur for Next week Delivery.

Only kit on the market to screen Cathepsin E inhibitors.

Description:

Cathepsin E (CTSE, EC: 3.4.23.34) is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that is found in highest concentration on the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of the gastric cancers. BioVision’s Cathepsin E Inhibitor Screening Kit utilizes the ability of Cathepsin E to cleave a synthetic MCA-based peptide substrate to release free MCA, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin E-specific inhibitor, the cleavage of the substrate is reduced/abolished resulting in decrease or total loss of the MCA fluorescence. This simple and high-throughput adaptable assay kit can be used to screen/study/characterize the potential inhibitors of Cathepsin E.

Applications: Screen/study/characterize potential inhibitors of Cathepsin E

Sample Typ:e

Alternate Name: CTSE Inhibitor Screening Kit (Fluorimetric)

Features and Benefits:

• Convenient & Rapid • High-throughput adaptable assay to screen/study/characterize the potential inhibitors of Cathepsin E • Cathepsin E inhibitor is included in the kit