Caspase-7 Inhibitor Drug Screening Kit (Fluorometric)

(No reviews yet) Write a Review
SKU:
K157-100
€465
Frequently bought together:

Description

Caspase-7 Inhibitor Drug Screening Kit (Fluorometric)is available at Gentaur for Next week Delivery.

.

Description:

Caspases have been shown to play a crucial role in apoptosis induced by various deleterious and physiologic stimuli. Inhibition of caspases can delay apoptosis, implicating a potential role in drug screening efforts. The Caspase-7 Inhibitor Drug Screening Kit provides an effective means for screening caspase inhibitors using fluorometric methods. The assay utilizes synthetic peptide substrate DEVD-AFC (AFC, 7-amino-4-trifluoromethyl coumarin). Active caspase-7 cleaves the synthetic substrate to release free AFC which can then be quantified by fluorometry. Compounds to be screened can directly be added to the reaction and the level of inhibition of caspase-7 activity can be determined by comparison of the fluorescence intensity in samples with and without the testing inhibitors.

Applications:

Sample Typ:e Cell samples treated with Caspase inhibitor drugs

Alternate Name:

Features and Benefits:

• Simple one-step procedure; takes only 1-1.5 hours • Fast and convenient • Inhibition of caspase-7 activity can be determined by comparison of the fluorescence intensity in samples with and without the testing inhibitors.

View AllClose

Additional Information

Size:
100 assays
Storage Conditions:
4°C-20°C
Shipping Conditions:
gel pack
Shelf life:
6-12 months
Category:
Apoptosis
View AllClose

0 Reviews

View AllClose