USP14 Polyclonal Antibody

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SKU:
CAC07270
Availability:
Next week delivery
£24,439.51
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Description

USP14 Polyclonal Antibodyis available at Gentaur for next week delivery.

Specificity:

Alternative Names: P54578

Immunogen: Recombinant Human Ubiquitin carboxyl-terminal hydrolase 14 protein (1-494AA)

Technical Notes: For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200

Restriction:

Comments: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4; Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).

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Additional Information

Species Reactivity:
Human, Mouse
Size:
100ug
Host:
Rabbit
Clonality:
Polyclonal
Concentration:
-20°C
Storage:
1 year
Expiry Date:
Ice packs
Shipping Condition:
Conjugation service and the corresponding secondary antibody are available.
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