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Description
UBP5 Antibodyis available at Gentaur for next week delivery.
Specificity: 8078
Alternative Names:
Immunogen: A synthesized peptide derived from human UBP5.
Technical Notes: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
Application: WB
Restriction:
Comments: Ice packs
Additional Information
Species Reactivity: |
Human,Mouse,Rat |
Size: |
100ug |
Host: |
Rabbit |
Clonality: |
Polyclonal |
Concentration: |
UBP5 |
Storage: |
1mg/ml |
Expiry Date: |
-20°C |
Shipping Condition: |
1 year |
Uniprot: |
P45974 |