Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) Mouse Monoclonal Antibody [Clone TYRP1/1986]

Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) Mouse Monoclonal Antibody [Clone TYRP1/1986] is available at Gentaur for Next Week Delivery.

Product Short Name:  Tyrosinase-Related Protein-1 (TYRP-1)

Other Names:

Product Gene Name: [TYRP-1]

Other Gene Names: 

Clonality:

Isotype: IgG2b, kappa

Clone:

Host: Mouse

Reactivity: Human

Specifity: It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

Purity: 

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: 

Storage Stability:  Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C.

Tested Application:  ELISA (EIA), Immunohistochemistry (IHC)-Formalin