Tp53 Polyclonal Antibody

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SKU:
CAC09185
Availability:
Next week delivery
  • TP53 Polyclonal Antibody
  • Tp53 Polyclonal Antibody
$33,066
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Description

Tp53 Polyclonal Antibodyis available at Gentaur for next week delivery.

Specificity:

Alternative Names: P10361

Immunogen: Recombinant Rat Cellular tumor antigen p53 protein (1-391AA)

Technical Notes: For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Application: ELISA, WB; Recommended dilution: WB:1:500-1:5000

Restriction:

Comments: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression By similarity. Interacts with GRK5

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Additional Information

Species Reactivity:
Rat, Mouse
Size:
100ug
Host:
Rabbit
Clonality:
Polyclonal
Concentration:
-20°C
Storage:
1 year
Expiry Date:
Ice packs
Shipping Condition:
Conjugation service and the corresponding secondary antibody are available.
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