SGMS1 Antibody

(No reviews yet) Write a Review
SKU:
CAF19964
Availability:
Next week delivery
£24,073.65
Frequently bought together:

Description

SGMS1 Antibodyis available at Gentaur for next week delivery.

Specificity: 259230

Alternative Names:

Immunogen: A synthesized peptide derived from human SGMS1.

Technical Notes: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

Application: WB

Restriction:

Comments: Ice packs

View AllClose

Additional Information

Species Reactivity:
Human,Mouse,Rat
Size:
100ug
Host:
Rabbit
Clonality:
Polyclonal
Concentration:
SGMS1
Storage:
1mg/ml
Expiry Date:
-20°C
Shipping Condition:
1 year
Uniprot:
Q86VZ5
View AllClose

0 Reviews

View AllClose