Phospho-Akt2 (Ser474) Antibody

Phospho-Akt2 (Ser474) Antibodyis available at Gentaur for Next week Delivery.

Description: AKT2 is a putative oncogenic protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore, AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.

Immunogen Sequence:Synthesized peptide derived from human Akt2 around the phosphorylation site of S474

Target Alternative Name:AKT2; RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta

Species Reactivities:Human, mouse , rat

Tag Line:Polyclonal antibody to detect endogenous levels of Akt2 protein phosphorylated at S474 in human, mouse and rat.

Formulation:In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Purification: Affinity-chromatography using epitope-specific immunogen

Application:WB, ELISA, IHC

Positive Control:WB: Mouse brain lysate, 293 cell lysate

Application And Usages:WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000

Handling:The antibody solution should be gently mixed before use