Langerin/CD207 (Marker of Langerhans Cells)

Langerin/CD207 (Marker of Langerhans Cells) is available at Gentaur for Next Week Delivery.

Product Short Name:  Langerin/CD207

Other Names: [C-type lectin domain family 4 member K; C-type lectin domain family 4 member K; C-type lectin domain family 4 member K; CD207 molecule; Langerin; CD_antigen: CD207]

Product Gene Name: [CD207]

Other Gene Names: [CD207; CD207; CLEC4K; CLEC4K]

Clonality:

Isotype: IgG1, kappa

Clone: [rLGRN/1821]

Host: Mouse

Reactivity: Human

Specifity: Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.

Purity:  Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: 

Storage Stability:  Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application:  ELISA (EIA)