KPTN Antibody

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SKU:
CAF20309
Availability:
Next week delivery
$127,877.47
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Description

KPTN Antibodyis available at Gentaur for next week delivery.

Specificity: 11133

Alternative Names:

Immunogen: A synthesized peptide derived from human KPTN.

Technical Notes: As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.

Application: WB

Restriction:

Comments: Ice packs

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Additional Information

Species Reactivity:
Human,Mouse,Rat
Size:
100ug
Host:
Rabbit
Clonality:
Polyclonal
Concentration:
KPTN
Storage:
1mg/ml
Expiry Date:
-20°C
Shipping Condition:
1 year
Uniprot:
Q9Y664
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