GTF2H5 Antibody

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SKU:
CAF20249
Availability:
Next week delivery
$32,571
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Description

GTF2H5 Antibodyis available at Gentaur for next week delivery.

Specificity: 404672

Alternative Names:

Immunogen: A synthesized peptide derived from human GTF2H5.

Technical Notes: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription. Necessary for the stability of the TFIIH complex and for the presence of normal levels of TFIIH in the cell.

Application: WB

Restriction:

Comments: Ice packs

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Additional Information

Species Reactivity:
Human,Mouse,Rat
Size:
100ug
Host:
Rabbit
Clonality:
Polyclonal
Concentration:
GTF2H5
Storage:
1mg/ml
Expiry Date:
-20°C
Shipping Condition:
1 year
Uniprot:
Q6ZYL4
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