ERP29 Polyclonal Antibody

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SKU:
CAC09067
Availability:
Next week delivery
$129,820.90
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Description

ERP29 Polyclonal Antibodyis available at Gentaur for next week delivery.

Specificity:

Alternative Names: P30040

Immunogen: Recombinant Human Endoplasmic reticulum resident protein 29 protein (40-251AA)

Technical Notes: For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Application: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Restriction:

Comments: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4; Proper protein folding and post-translational modifications are essential for secretory protein export out of the endoplasmic reticulum. This task is accomplished by chaperone proteins such as protein disulfide isomerase (PDI), GRP94, and BiP. A recently characterized protein, designated ERp29, is closely related to these chaperone proteins and appears to be upregulated during ER stress conditions. ERp29 is a soluble 259-residue protein that is localized to the lumen of the endoplasmic reticulum in all mammalian cells. Research has shown that there are two primary domains within ERp29. The first is the C-terminal region that is a novel, all helical, fold that is most likely involved with ERp29 retention to the ER. The second is the N-terminal region that resembles that of PDI’s thioredoxin module. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER.

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Additional Information

Species Reactivity:
Human
Size:
100ug
Host:
Rabbit
Clonality:
Polyclonal
Concentration:
-20°C
Storage:
1 year
Expiry Date:
Ice packs
Shipping Condition:
Conjugation service and the corresponding secondary antibody are available.
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