ECD Antibody

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SKU:
CAF20171
Availability:
Next week delivery
$32,571
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Description

ECD Antibodyis available at Gentaur for next week delivery.

Specificity: 11319

Alternative Names:

Immunogen: A synthesized peptide derived from human ECD.

Technical Notes: Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP (PubMed:16849563, PubMed:23880345). May be involved transcriptional regulation. In has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes (PubMed:19919181, PubMed:9928932). Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins (PubMed:19640839). The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex (PubMed:26711270). May play a role in regulation of pre-mRNA splicing (PubMed:24722212).

Application: WB

Restriction:

Comments: Ice packs

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Additional Information

Species Reactivity:
Human,Mouse
Size:
100ug
Host:
Rabbit
Clonality:
Polyclonal
Concentration:
ECD
Storage:
1mg/ml
Expiry Date:
-20°C
Shipping Condition:
1 year
Uniprot:
O95905
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