DHX36 Antibody

(No reviews yet) Write a Review
SKU:
CAF20147
Availability:
Next week delivery
$127,877.47
Frequently bought together:

Description

DHX36 Antibodyis available at Gentaur for next week delivery.

Specificity: 170506

Alternative Names:

Immunogen: A synthesized peptide derived from human DHX36.

Technical Notes: Proposed to have a global role in regulating mRNA expression including transcriptional regulation and mRNA stability. Binds with high affinity to and resolves tetramolecular RNA and DNA quadruplex structures. Unwinds intramolecular quadruplexes derived from the ZIC1 and the MYC promoters. Binds to quadruplex structures in the promoters of YY1 and ALPL genes and regulates their expression. Binds to telomerase RNA template component (TERC) 5'-end (nucleotides 1-43) and unwinds an internal quadruplex formation in TERC 5'-end to promote P1 helix formation; the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regulation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis. May play a role in ossification.

Application: WB

Restriction:

Comments: Ice packs

View AllClose

Additional Information

Species Reactivity:
Human,Mouse,Rat
Size:
100ug
Host:
Rabbit
Clonality:
Polyclonal
Concentration:
DHX36
Storage:
1mg/ml
Expiry Date:
-20°C
Shipping Condition:
1 year
Uniprot:
Q9H2U1
View AllClose

0 Reviews

View AllClose